The anti-mullerian hormone (AMH) test is part of IVF treatment. Before you begin IVF treatment, your fertility doctor will test your AMH levels to determine whether you’re a good candidate. Low AMH levels may indicate diminished ovarian reserve and a low number of eggs produced. High AMH levels fall within the range exhibited by fertile women. Your IVF specialist will test AMH levels, among other evaluations, to make sure you’re ready for ovarian stimulation.
What Is AMH?
The anti-mullerian hormone is naturally produced by the cells in the ovary. AMH levels are high during your reproductive years, rising from birth and peaking in your mid-20s. The levels begin to drop after that as the ovarian reserve is depleted. AMH becomes indetectable at menopause. Your AMH levels may also decline due to medical conditions affecting your ovaries and reproductive system. Low levels can make it difficult to ovulate or conceive.
AMH levels match the number of eggs (oocytes) harvested after IVF stimulation. Your IVF specialist can measure AMH levels to predict ovarian response during treatment. AMH levels can also help fertility doctors predict the likelihood of live birth after IVF. The hormone can provide telltale signs of menopause if you have low levels. AMH is usually low or undetectable about five years before menopause.
Here’s why AMH levels matter in IVF:
1. Assessing Ovarian Reserve
AMH-level tests are designed to assess ovarian reserve. The hormone is high in reproductive women and diminishes as you get older. AMH levels can help predict the number of eggs left in your reserve. The test doesn’t determine the quality of eggs, so you can conceive despite low AMH levels. Conception relies on many factors, and one healthy egg is all you need for fertilization. AMH level tests will determine if you have the ideal number of oocytes for IVF.
2. Predicting IVF Success
Fertility doctors can use AMH-level tests to determine stimulation protocols for IV treatment. The blood test is one of many evaluations your fertility specialist will complete before recommending IVF. Your doctor will likely test for markers like the follicle-stimulating hormone, estradiol, and antral follicle count. Low AMH levels suggest a poor response to stimulation and poor results. High AMH levels may provide more success in those undergoing IVF treatment.
What Is The Best AMH Level?
According to research AMH levels of 4-6.8 ng/mL provide optimal results and 2.2-4 ng/mL offer satisfactory results. If your AMH level is low you’re more likely to exhibit a low response to ovarian hyperstimulation. Fertility experts have a standard interpretation. High AMH levels start from 3.0 ng/ml but don’t predict the chance of conception. Here’s more about the AMH test results and interpretation:
- Below 0.5 ng/mL:Low AMH levels are exhibited by women with fewer eggs than others and predict difficulty getting pregnant through IVF treatment.
- 5 – 1-.0 ng/mL: Low AMH levels indicate a limited egg supply and a short window of opportunity to have a child via in-vitro.
- 0 – 3.5 ng/mL:AMH levels above 1.0 ng/mL are more likely to provide successful responses to IVF treatment.
- Above 3.5 ng/mL:If your levels are above 3.5 ng/mL, you have an ample supply of eggs and a higher chance of successful treatment.
AMH levels vary by age based on the number of eggs left in your ovarian reserve. If you’re 45 years or older, low levels are expected but shouldn’t drop below 0.5 ng/mL. Young women below 25 years should have AMH levels above 3 ng/mL. Having levels below 1.6 ng/mL denotes a low number of eggs produced during IVF stimulation. 1.0 to 4.0 ng/mL is the ideal range you should maintain when looking to get pregnant through IVF treatment.
Work With an IVF Specialist
AMH is a hormone produced by the ovaries. If the hormone levels drop, it may suggest a low ovarian reserve. Higher levels indicate an ample number of eggs. AMH levels don’t assess egg quality, so having high levels of the hormone doesn’t predict conception. Women can also get pregnant despite having lower levels of the AMH hormone. You need an experienced fertility doctor for comprehensive evaluation before an IVF cycle.
Working with a reputable IVF specialist can help you assess your ovarian reserve and other aspects that influence fertility. The goal is to treat underlying conditions and boost your chances of conception. Look for leading fertility clinics that can perform a comprehensive evaluation and provide custom treatment based on your needs. Women often have the potential to get pregnant regardless of the AMH levels, provided they have healthy, high-quality eggs in their reserve.